Articles in Longevity
Biohacking Guide: Science-Based Protocols for Human Optimization Research
A comprehensive research guide to biohacking protocols — from NAD+ and longevity compounds to nootropics, slee…
Berberine vs Metformin: Mechanisms, Research Overlap, and Key Differences
Both compounds activate AMPK and affect glucose metabolism, but the research base differs significantly. We co…
Urolithin A Research: Mitophagy Activation and Muscle Endurance Findings
Urolithin A is a gut-derived metabolite studied for mitophagy and skeletal muscle endurance. We break down the…
Sleep Optimization for Recovery: What the Science Says
Sleep is the most important recovery tool. Here's the research on sleep stages, timing, and optimization.
Red Light Therapy: What the Research Shows
Red and near-infrared light therapy has growing research behind it. Here's a grounded look at the evidence.
Gut Microbiome Optimization: What the Research Recommends
A healthy gut microbiome affects everything from immunity to mood. Here's what the research actually recommend…
Zone 2 Cardio and Mitochondrial Health: Science Guide
Zone 2 training builds mitochondrial density and metabolic flexibility. Here's the research behind it.
Exogenous Ketones and Performance: Research Review
Ketone supplements have been studied for endurance performance and cognitive function. Here's what the evidenc…
Peptide Therapy Research: What Clinics Are Studying
Research peptides are being studied in clinical settings. Here's an overview of current research directions.
Peptides in Biohacking: Research Compounds Being Self-Experimented
Research peptides have entered biohacking communities. Here's an overview of which compounds are being studied…
Biohacking 101: What It Is and Where to Start
Biohacking covers everything from sleep optimization to research compounds. Here's a grounded introduction.
Lithium Microdosing Research: Neuroprotection, GSK-3 Inhibition, and Longevity Signals
Trace lithium in drinking water correlates with lower dementia rates in epidemiological data. We review the GS…
Time-Restricted Eating vs Caloric Restriction: Longevity Mechanisms and Head-to-Head Research
Are TRE benefits driven by caloric restriction or circadian signaling? We compare the mechanisms and human stu…
Phosphatidylcholine and Brain Aging: Choline Metabolism, Cognitive Decline, and Research Evidence
Phosphatidylcholine is the dominant phospholipid in neuronal membranes. We review what choline metabolism rese…
Biological Age Testing: Comparing Epigenetic Clocks, Telomere Length, and Blood Biomarker Panels
Epigenetic clocks, telomere assays, and biomarker panels all claim to measure biological age. We compare their…
Spermidine Research: Autophagy Induction, Dietary Sources, and Longevity Biomarkers
Spermidine induces autophagy and has shown cardiovascular and cognitive benefits in observational and early cl…
Hyperbaric Oxygen Therapy and Cellular Aging: What Controlled Studies Show
HBOT has been flagged as a longevity tool after a 2020 Israeli study on telomere length. We examine the eviden…
Rapamycin Longevity Research: mTOR Inhibition, Dosing Protocols, and Study Limitations
Rapamycin extends lifespan in model organisms via mTOR inhibition. We review the human-relevant data, proposed…
VO2 Max and Longevity: The Research Connection
VO2 max is one of the strongest predictors of lifespan. Here's the research and how to improve it.
Longevity Science: What We Know About Extending Healthspan
The science of living longer and healthier is advancing rapidly. Here's what the current research actually say…
Intermittent Fasting and Autophagy: The Science Explained
Fasting triggers autophagy, the cellular cleanup process. Here's the research on timing, depth, and benefits.
NAD+ and Aging: What Precursor Supplements Are Being Studied
NAD+ levels decline with age. Here's the research on NMN and NR precursors and what studies show.
The Hallmarks of Aging: Biology of Why We Age
Aging isn't random. Here's the current scientific framework for the 12 hallmarks of biological aging.
Sauna Use for Recovery and Longevity: Research Summary
Sauna use has more clinical research behind it than most recovery tools. Here's the evidence summary.